There are many references to false cell lines within the scientific literature, beginning with the pioneering work of Stanley Gartler and Walter Nelson-Rees.
A full list of these references can be found here, in ICLAC’s Database of Cross-Contaminated or Misidentified Cell Lines.
- Masters JR, Alston-Roberts C, Barrett T, Burnett EC, Cooper JR, Dirks WG, Freshney RI, Healy L, Kerrigan L, Kohara A, Korch C, MacLeod RA, Nakamura Y, Nims RW, Reid YA, Storts DR, Capes-Davis A (2012) Cell-line authentication: End the scandal of false cell lines. Nature 492: 186. PMID: 23235867.
- Capes-Davis A, Alston-Roberts C, Kerrigan L, Reid YA, Barrett T, Burnett EC, Cooper JR, Freshney RI, Healy L, Kohara A, Korch C, Masters JR, Nakamura Y, Nims RW, Storts DR, Dirks WG, Macleod RA, Drexler HG (2013) Beware imposters: MA-1, a novel MALT lymphoma cell line, is misidentified and corresponds to Pfeiffer, a diffuse large B-cell lymphoma cell line. Genes Chromosomes Cancer 52: 986-8. PMID: 23907998.
- Capes-Davis A, Dirks WG, MacLeod RA, Uphoff CC (2014) Quality Matters: Cell Lines and their Use in Research. GIT Laboratory Journal Europe 17 (1-2): 12-13. See Journal website.
- Dirks WG, Kerrigan L, Peluso C, Wilder C (2014) Choose Wisely: Obtaining Cell Lines from Reliable Sources. GIT Laboratory Journal Europe 17 (3-4): 22-24. See Journal website.
- Cooper J, Burnett E, MacLeod RA, Nims R, Moy E, Capes-Davis A (2014) Cell Banking: Reliable Storage of Authentic Cell Lines. GIT Laboratory Journal Europe 17 (5-6): 18-20. See Journal website.
- The International Cell Line Authentication Committee (2014) Cell Line Cross-Contamination: WSU-CLL is a known derivative of REH and is unsuitable as a model for chronic lymphocytic leukemia. Leukemia Res, Epub May 23. PMID: 24923861.
- The International Cell Line Authentication Committee (2014) New Resources for an Old Problem: Cell Line Cross-Contamination. In Vitro Report 48.3. See journal website.
- Nardone RM, MacLeod RA, Capes-Davis A (2016) Cancer: Authenticate new xenograft models. Nature 532: 313. PMID: 27127813.
Further Reading – Community Information
Would you like to read more about the topic without wading through the technical details? Suggestions can be found here.
Further Reading – Scientific Information
Are you a scientist who would like more information from a technical viewpoint? We suggest guidelines for Good Cell Culture Practice, good reviews on misidentified cell lines, and articles on human cell line authentication, testing of non-human cell lines, and microbial contamination.