Version 10 of the ICLAC Register of Misidentified Cell Lines was released on 25 March 2020. ...

On the world wide web, authorized sources offer human cell lines that may be used as model systems for addressing specific scientific questions. Such authorized sources offer unambiguous proof of the authenticity of these cell lines via STR profiling or ...

In May 2016, ICLAC wrote a letter to US Vice President Joe Biden and the National Cancer Advisory Board, urging that common principles and requirements are adopted for training and quality assurance testing of research materials. ...

The Cellosaurus is a knowledge resource on cell lines. It attempts to describe all cell lines used in biomedical research. For each cell line (currently ~120,000) the Cellosaurus provides a wealth of information. ...

CLASTR is a STR similarity search tool that allows to compare one or more STR profiles from human, dog or mouse cell lines with those available in the Cellosaurus (~7000 profiles). ...

Leibniz Institute DSMZ operates a user-friendly interface to query its database of STR profiles, brought together in collaboration with cell banks ATCC, JCRB, and RIKEN as a human cell line cross-contamination initiative. ...

The Cell Line Integrated Molecular Authentication (CLIMA) database is the result of an integration effort aimed at including all certified STR profiles of human cell lines in a unique database. Its main feature is cell line identification according to the ...

As part of their continuing efforts to characterize and authenticate the cell lines in the Cell Biology collection, ATCC has developed a comprehensive database of short tandem repeat (STR) DNA profiles for all of their human cell lines. ...

The NCBI BioSample database archives STR profiles and descriptions for several thousand cell lines, as provided by cell line repositories. The database is administered by the US National Library of Medicine, National Institutes of Health. ...

Author | Erin Hall, ICLAC member Informing the research community about instances of cell line misidentification and cross-contamination is one of the core missions of ICLAC, but our mission doesn’t just focus on human cell lines. In this case study, ...