Author | Erin Hall, ICLAC member This case study will delve into the history and identity of Chang Liver. We hope it will serve as a notice to researchers who continue to use the cell line incorrectly as an in ...

Author | Amanda Capes-Davis, ICLAC member WSU-CLL is a cell line that was thought to be established from chronic lymphocytic leukemia. In 2002, it was found that WSU-CLL is actually REH, a cell line from B-cell precursor acute lymphoblastic leukemia.Citation ...

Research organizations have an important role to play in promoting and improving good cell culture practice. This role includes providing cell culture training and developing policies to ensure that research using cell lines is reliable and reproducible. A model policy ...

This worksheet for human cell line authentication can help scientists to determine if STR profiles from two cell line samples are related. The worksheet uses match criteria from a Standard for human cell line authentication.  To cite the match criteria or learn more, please ...

This checklist was written as a resource for scientists that write or review manuscripts and grant applications.  The list can be used to help determine if the cell lines used for this work meet acceptable quality requirements. The checklist is made available ...

This document was written to set out the essential steps for authenticating human cell lines. The Guide focuses on short tandem repeat (STR) profiling, as a widely used and accepted authentication method.  The Guide includes sections on: Preparing starting material for ...

This document takes the most important things a scientist needs to know about authenticating cell lines and squeezes that information into two pages for quick and easy reference. The document summarizes what you need to consider when: Planning a project or grant ...

This document was written to help a scientist find a unique name for a new cell line. ICLAC has noticed an increasing number of cell lines with identical names but coming from different donors.  To help address this problem, we set out essential ...

Common cell culture terms are defined in the Guidelines for the Use of Cell Lines in Biomedical Research, which is available online.  ICLAC has included additional definitions as part of its Terms of Reference, some of which are copied here. See ICLAC Terms ...