This document was written to set out the essential steps for authenticating human cell lines. The Guide focuses on short tandem repeat (STR) profiling, as a widely used and accepted authentication method.  The Guide includes sections on: Preparing starting material for ...

This document was written to set out the essential steps for authenticating mouse cell lines. The Guide focuses on short tandem repeat (STR) profiling, as a widely used and accepted authentication method.  The Guide includes sections on: Preparing starting material for ...

Watch The Hidden World of Cell Lines on YouTube Visit the companion page for scientific background and information The Hidden World of Cell Lines video is a short, engaging introduction to cell lines and their problems. It is designed for ...

Version 11 of the ICLAC Register of Misidentified Cell Lines was released on 8 June 2021. ...

Version 10 of the ICLAC Register of Misidentified Cell Lines was released on 25 March 2020. ...

Author | Erin Hall, ICLAC member Informing the research community about instances of cell line misidentification and cross-contamination is one of the core missions of ICLAC, but our mission doesn’t just focus on human cell lines. In this case study, ...

Author | Erin Hall, ICLAC member This case study will delve into the history and identity of Chang Liver. We hope it will serve as a notice to researchers who continue to use the cell line incorrectly as an in ...

Author | Amanda Capes-Davis, ICLAC member WSU-CLL is a cell line that was thought to be established from chronic lymphocytic leukemia. In 2002, it was found that WSU-CLL is actually REH, a cell line from B-cell precursor acute lymphoblastic leukemia.Citation ...

Common cell culture terms are defined in the Guidelines for the Use of Cell Lines in Biomedical Research, which is available online.  ICLAC has included additional definitions as part of its Terms of Reference, some of which are copied here. See ICLAC Terms ...